Inducedpluripotentstemcells相关论文
Non-human primates play a key role in the preclinical validation of pluripotent stem cell-based cell replacement therapi......
Generation of male germ cells from induced pluripotent stem cells (iPS cells): an in vitro and in vi
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Objective: Salvia miltiorrhiza,a well-known traditional Chinese medicine,is commonly used to treat some neurological dis......
Exosomes secreted by human-induced pluripotent stem cell-derivedmesenchymal stem cells repair osteoc
Purpose: The purpose of this study was to investigate the chondrogenic features of exosomes secreted by human-induced pl......
Object: Melatonin,a lipophilic molecule mainly synthesized in the pineal gland,has properties of antioxidation,antiinfla......
In situ implantation of photoactive hydrogel with exosomes secreted by human-induced pluripotent ste
Purpose: To investigate cartilage regeneration effects of exosomes secreted by human-induced pluripotent stem cell-deriv......
Valproic Acid-induced Hepatotoxicity in Alpers Syndrome is Associated with mPTP Opening Dependent Ap
Valproic acid (VPA) is widely used to treat epilepsy, migraine, chronic headache, bipolar disorder,and as adjuvant chemo......
Cleft lip/palate (CLP) is a group of ectodermal dysplasia that includes cleft lip,cleft palate,and both together.The sub......
Assessing the roles of cardiac INa and ITo currents in the cellular mechanism of the Brugada syndrom
Background: Brugada syndrome(BrS)is an inherited cardiac condition characterized by signature changes in the electrocard......
Nodal regulates the differentiation of iPS cells to male germ cells via Smad2/3,Oct4 and Foxh1 activ
Objective: The differentiation of male germ cells from iPS cellsprovides an ideal model for unveiling molecular mechanis......
In vertebrates,perception of sound,motion,and balance is mediated through sensorineural hair cells and spiral ganglion n......
Generation of human β-thalassemia induced pluripotent stem cells from amniotic fluid cells with non-
Objective Induced pluripotent stem cells (iPSCs) derived from somatic cells of patients represent a powerful tool for bi......
Modeling long QT syndrome with cardiomyocytes derived from patient-specific induced pluripotent stem
Aims Inherited long QT syndrome (LQTS) is characterized by QT-interval prolongation and lethal arrhythmia resulting from......
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双相障碍目前已成为全球性的公共健康问题之一,由于缺乏准确可靠的研究手段,其发病机制尚未完全清楚。近年来,诱导性多能干细胞(induce......
Somatic cells can be successfully reprogrammed into pluripotent stem cells by the ectopic expression of defined tran......
Neural progenitor cells from human induced pluripotent stem cells generated less autogenous immune r
The breakthrough development of induced pluripotent stem cells(iPSCs)raises the prospect of patient-specific treatment f......
Transfer of mitochondria from mesenchymal stem cells derived from induced pluripotent stem cells att
Mitochondrial dysfunction in neurons has been implicated in hypoxia-ischemia-induced brain injury. Although mesenchymal ......
microRNA is important for maintaining characteristics of embryonic stem cells,and microRNA302a (MiR-302a) has been shown......
脱发性疾病是临床上常见的一组影响美容、心理和健康的疾病.目前,脱发性疾病的发病机制仍不甚清楚.毛囊结构、毛乳头细胞及毛囊干......
大骨节病自发现以来,尽管其流行趋势已显著控制,但其病因、发病机制一直是世界性医学谜团之一。面对大骨节病人体软骨组织和细胞难以......